NHP Disease Models

 

We provide our clients a full service “hospital”, plus a multi-functional research platform which features in-house and/or contracted well known scientific and clinical experts in various fields, using diseased models, particularly NHP.

First of all, we have mature technologies and know-how in animal disease modeling. Currently our manmade and/or natural-occurring disease models are mainly in the following areas:

l  Parkinson’s Disease

Ø   MPTP-induced Parkinsonism: Including systemically (acute and chronic) and unilateral lesioned (ICA) Parkinsonism

Ø   Dyskinesia Model: Levodopa-induced dyskinesia

Ø   Other Toxin Induced Neurodegeneration and Parkinsonism: Toxins including pesticides, LPS and others

Ø   Gene Targeted Parkinsonism: Including transgene delivery of targeted genes, e.g. a-synuclein and Parkin, and gene knock-down with siRNA  

l  Ataxia and Huntington disease

l  Multiple sclerosis

l  Stroke

l  Nature-occurring type II diabetes, preconditioning type II diabetes, and drug-induced type I diabetes with and without complications

l  Obesity

l  Nature-occurring Hyperinsulinemia, Hypercholesterolemia, Metabolic Syndrome, Arteriosclerosis

 

  Models
 
 
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